Fabian Cancellara is going to win the prologue. He's just super amazing. He's also one of my favorite riders, so I'm a bit biased, but since he's like the greatest time trialist, I think he has a good chance. I also wouldn't be surprised if Lance won. He's awesome like that.
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Although I don't like him, I think Levi Leipheimer is going to win the whole race. He's a boring rider and he's not cute so I'd rather have someone else win but.....it's his race. Leipheimer is from California so he especially wants to win this race and with his team, he'd almost have to throw it away.

George Hincapie is going to win the hardest stage. He excels at those type of stages.
More predictions might come later, it depends. I can't wait to watch, or I guess read, the race.